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SaProtHub/Dataset-ACE2_Omicron_XBB.1.5_binding_affinity

Description This dataset contains ACE2 binding affinities of mutant SARSCoV-2 XBB.1.5 variants amino acid sequences. Protein Format: AA sequence Splits traing: 3388 valid: 408 test: 418 Related paper The dataset is from Deep mutational scans of XBB.1.5 and BQ.1.1 reveal ongoing epistatic drift during SARSCoV-2 evolution. Label Label means delta mutation effect (ACE2 binding affinities) compre to wildtype, ranging from minus infinity… See the full description on the dataset page: https://huggingface.co/datasets/SaProtHub/Dataset-ACE2_Omicron_XBB.1.5_binding_affinity.

sourceHugging Facemitupdated 2y agoView on Hugging Face
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Description

This dataset contains ACE2 binding affinities of mutant SARSCoV-2 XBB.1.5 variants amino acid sequences.

Protein Format: AA sequence

Splits

traing: 3388

valid: 408

test: 418

Related paper

The dataset is from Deep mutational scans of XBB.1.5 and BQ.1.1 reveal ongoing epistatic drift during SARSCoV-2 evolution.

Label

Label means delta mutation effect (ACE2 binding affinities) compre to wildtype, ranging from minus infinity to positive infinity. Zero means no affinity, lager means higher affinity and smaller means lower affinity.