Modelpublic

pyaging/retroelementagev2

sourceHugging Faceupdated 8d agoView on Hugging Face

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Model Card

retroelementagev2

Composite Retroelement-Age V2 extends the retroelement annotation to CpGs compatible across EPIC v1.0 and v2.0 and was trained by 10-fold-cross-validated elastic net.

Model weights retain the original authors' terms; the pyaging software license does not relicense them.


Predicts	chronological age
Species	Homo sapiens
Tissue	whole blood
Data type	DNA methylation
Model type	elastic net regression
Year	2024

Use with pyaging

python

import pyaging as pya

pya.pred.predict_age(adata, ["retroelementagev2"])

Browse every clock in the pyaging Clock Catalogue.

Citation

Ndhlovu, Lishomwa C., et al. "Retro-age: A unique epigenetic biomarker of aging captured by DNA methylation states of retroelements." Aging Cell 23 (2024): e14288.

https://doi.org/10.1111/acel.14288